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Jul 1, 2025 · Zhao et al. identified a novel E3 ligase RED and its E2 partner UBC32 which mediates ethylene-induced degradation of ethylene receptors ETR3 via the ERAD pathway in Rosa hybrida and Solanum ...
该基因编码 E2 泛素结合酶家族的成员。 编码的蛋白质与小鼠和大鼠对应物具有 100% 的序列同一性，这表明该酶在真核生物中高度保守。 已为该基因发现了编码相同蛋白质的多个可变剪接转录物变体。 [RefSeq 提供，2013 年 6 月]
The ubiquitin–proteasome system (UPS) plays a pivotal role in determining protein fate, regulating signal transduction, and maintaining cellular homeostasis. Protein ubiquitination, a key post-translational modificati...
APOE基因检测结果为E2/E3，表示携带了一个 E2等位基因 和一个 E3等位基因。 APOE基因参与脂蛋白代谢，与心血管疾病、阿尔茨海默病等风险相关。 E2/E3型属于 相对常见的杂合基因型，整体健康风险较低，但仍需结合其他指标和生活方式综合评估。
Jan 15, 2026 · Molecular function for UBE2E3Gene according to GENATLAS Biochemistry: ubiquitin conjugating enzyme E2E3,homologous to yeast UBC4/5,expressed in skeletal muscle UBE2E3
Apr 29, 2025 · The ubiquitin–proteasome system (UPS) plays a pivotal role in determining protein fate, regulating signal transduction, and maintaining cellular homeostasis. Protein ubiquitination, a key post-translati...
Dec 18, 2023 · Chrustowicz, Sherpa, et al. decipher evolutionarily conserved determinants of an exquisitely specific E3-E2 partnership ubiquitylating globular substrates. Cryo-EM visualizes a flexing GID E3 superassem...
