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Complete information for CDKN1C gene (Protein Coding), Cyclin Dependent Kinase Inhibitor 1C, including: function, proteins, disorders, pathways, orthologs, and expression.
CDKN1C 编码蛋白p57KIP2，p57KIP2 是细胞周期依赖性激酶抑制因子家族成员，对细胞增殖起负调节作用。 该基因既是一个可能的抑癌基因，也是一个潜在的负调控胎儿生长的基因。
关于 CDKN1C Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:2,883,218-2,885,775 (from NCBI) This gene has 7 transcripts (splice variants), 1 gene allele, 219 orthologues, 2 paralogues and is associated wi...
CDKN1C（Cyclin-Dependent Kinase Inhibitor 1C）是一种重要的细胞周期调控基因，属于CIP/KIP家族（CDK抑制蛋白家族），该家族还包括CDKN1A（p21）和CDKN1B（p27）。
Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlation.
CDKN1C位于遗传位点11p15.5，其特征是具有显着的区域烙印，仅导致母体等位基因转录。 CDKN1C转录的控制还与其他机制相关，包括DNA甲基化和特定的组蛋白甲基化/乙酰化。
There was no association between germline CDKN1C mutations and risk of embryonal tumors. No CDKN1C mutations were identified in 6 non-BWS patients with overgrowth and Wilms tumor. Algar et al. (1999) reported 2 patien...
本文将详细介绍CDKN1C基因在细胞中的表达调控机制，包括其位置、功能、以及与其他分子的相互作用，帮助理解该基因在细胞周期调控中的重要性。
Diminished CDKN1C expression is associated with loss of methylation of CpG & H3K9 at DMR-LIT1, & is involved in esophageal cancer. DMR-LIT1 epigenetically regulates CDKN1C expression through histone modifications at D...
Cyclin-dependent kinase inhibitor 1C is a protein in humans that is encoded by CDKN1C gene. Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to ...
