HepaRG细胞系

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HepaRG™细胞-原代肝细胞替代模型-赛默飞 | Thermo Fisher Scientific ...

Gibco HepaRG细胞是衍生自人肝原代细胞系的终末分化肝细胞,保留了原代人肝细胞的许多特征。 HepaRG细胞包含一个生物学上相关的替代模型,该模型显示了许多原代人肝细胞的特征,包括关键代谢酶(I和II期),核受体(CAR、PXR和AhR)和药物转运蛋白的形态和表达。

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HepaRG - Wikipedia

HepaRG cells are bipotent progenitors, capable of differentiating into both biliary and hepatocyte lineages. In culture, they are organized in well-delineated trabeculae with many bright canaliculi-like structures und...

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HepaRG 细胞的生物学特点及其应用-丁香实验

Oct 11, 2017 · 这些研究说明结合细胞功能和细胞毒性的研究方法来研究药物肝脏毒性的机制时,通过在 HepaRG细胞中检测结构相关的化合物,使 HepaRG细胞可作为研究肝毒性的细胞筛选模型。

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HepaRG Cells and Supplements - Thermo Fisher Scientific - US

HepaRG cells are terminally differentiated hepatic cells (derived from a human liver progenitor cell line) that retain many characteristics of primary human hepatocytes. HepaRG cells are provided in a convenient cryop...

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分化的 HepaRG - MilliporeSigma

说明 General description HepaRG 是一种人类肝癌细胞系,最初来源于一名诊断为肝癌和丙型肝炎的女性患者。 这些细胞具有假二倍体核型,并已被表征为卵形管状双能肝细胞系,在 DMSO 存在下具有分化为胆管和肝细胞谱系的能力。