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Jan 14, 2026 · Complete information for AS3MT gene (Protein Coding), Arsenite Methyltransferase, including: function, proteins, disorders, pathways, orthologs, and expression.
May 3, 2025 · Gene target information for AS3MT - arsenite methyltransferase (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
AS3MT（砷甲基转移酶，Arsenic Methyltransferase）是一个参与砷代谢的关键基因，属于甲基转移酶基因家族。 它的主要功能是将无机砷（如砷酸盐和亚砷酸盐）通过甲基化转化为毒性较低的单甲基砷酸（MMA）和二甲基砷酸（DMA），从而帮助机体解毒。
AS3MT ... Arsenite methyltransferase is an enzyme that in humans is encoded by the AS3MT gene. [5][6]
Dec 10, 2024 · AS3MT（arsenite methyltransferase）基因位于人类染色体10的q24.32区段，是一个编码小分子甲基转移酶的基因。 其主要功能是参与砷的代谢过程，通过甲基化反应将无机砷转化为较不毒的有机形式。 AS3MT基因也被称为CYT19，并且在OMIM数据库中的编号为611806。
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]). [supplied by OMIM, Mar 2008]
After cloning the human AS3MT cDNA, we annotated the human gene and resequenced its 5′-flanking region, exons, and splice junctions using 60 DNA samples from African-American (AA) and 60 samples from Caucasian-America...
Nov 29, 2023 · AS3MT重组蛋白的应用 AS3MT重组蛋白对于理解砷代谢和 砷中毒 的分子机制至关重要。 这些研究有助于揭示AS3MT在 细胞代谢 和砷相关疾病中的作用，为开发治疗策略提供了可能性。
The human enzyme As (III) S-adenosylmethionine methyltransferase (AS3MT) catalyzes arsenic biotransformations and is considered to contribute to arsenic-related diseases.
砷酸盐甲基转移酶活性和甲基砷酸盐甲基转移酶活性。 预测涉及砷酸醋酸盐代谢过程、甲基化以及毒素代谢过程。 预测在响应含砷物质的上游或内部发挥作用。 位于线粒体中。 与人类的AS3MT (砷酸盐甲基转移酶)正链同源。 [由基因组资源联盟，2022年4月提供]
