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Jan 15, 2026 · GeneCards Summary for IGF1 Gene IGF1 (Insulin Like Growth Factor 1) is a Protein Coding gene. Diseases associated with IGF1 include Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency and I...
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. [5] In the...
综合检测GH的分泌活性、IGF-1的直接效应及IGFBP-3的稳定性,为儿童矮小症、GHD及治疗监测提供了全面依据。 其临床价值不仅在于精准诊断,更在于优化治疗方案、降低治疗风险,是内分泌疾病管理的重要工具。
The present review article provides a concise overview of key scientific developments in the research area of IGF and highlights a number of more recent findings, including its nuclear migration and its interaction wi...
Jan 8, 2025 · IGF1基因的基本功能 IGF1基因,全名为胰岛素样生长因子1,位于12号染色体长臂23.2区段。这个基因的主要任务是编码一种叫做胰岛素样生长因子1的蛋白质,简称IGF-I。IGF-I在体内的作用非常广泛,主要涉及到细胞的生长、分化和代谢调控。
胰岛素样生长因子1(IGF-1)是由人类基因IGF1编码的单链多肽,分子量约7.6-9.0 kDa。其分泌主要受生长激素调控,肝脏是主要合成器官。该蛋白质通过激活IGF1受体启动PI3K-AKT和Ras-MAPK等信号通路,在骨骼生长、肌肉合成、糖原调控及神经发育中起核心作用。动物双歧杆菌乳亚种BL‑11能够促进IGF-1的产生 ...
胰岛素样生长因子-1 (insulin-like growth factor 1, IGF-1)是一种多功能细胞增殖调控因子,广泛分布于各个组织当中,在细胞的分化增殖个体的生长发育中具有重要的作用。