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Jan 15, 2026 · IGF2 is a protein coding gene that encodes a growth factor involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and associated with several disorders and...
胰岛素样生长因子2（Igf2）是人类最早发现的内源性印迹基因，其表达受表观遗传调控而不遵循 孟德尔遗传规律 [5]，作为银罗素综合征3型（SRS3）的致病基因，呈现母系印记父系表达特征 [8]。该基因编码的蛋白质具有促进细胞增殖、胚胎发育及肿瘤生长的多重功能，父源单等位基因表达是其典型 ...
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized neutral peptide believed to be secreted by the liver ...
Jun 1, 2022 · IGF-2基因是一种与IGF-1基因同源的胰岛素样生长因子，参与胚胎发育、成骨、肿瘤等过程。本文介绍了IGF-2基因的发现和命名历史，以及它与IGF-1基因的蛋白结构差异和生理作用差异。
In the 30 years since the first report of parental imprinting in insulin-like growth factor 2 (Igf2) knockout mouse models, we have learnt much about the structure of this protein, its role and regulation. Indeed, man...
Jan 8, 2025 · IGF2基因的功能 IGF2基因主要负责编码胰岛素样生长因子2（IGF-II），这是一种在胚胎发育和出生后生长过程中起关键作用的肽类激素。IGF-II与胰岛素样生长因子1（IGF-I）相似，但它的表达主要在胎儿期，而IGF-I则在成年期更为活跃。 IGF-II的主要功能包括：
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IGF2 （Insulin-like Growth Factor 2），编码 胰岛素样生长因子 2，是一种在胚胎发育和生长调控中起决定性作用的肽类激素。 IGF2 是表观遗传学中 基因印记 (Genomic Imprinting) 现象的经典模型：在正常组织中，它主要表现为 父系表达 （即只有来自父亲的等位基因转录 ...
胰岛素样生长因子 2： 该基因编码多肽生长因子胰岛素家族的成员，参与发育和生长。它是一个印记基因，仅从父系等位基因表达，该位点的表观遗传变化与肾母细胞瘤、Beckwith-Wiedemann 综合征、横纹肌肉瘤和 Silver-Russell 综合征有关。存在通读 INS-IGF2 基因，其 5' 区域与 INS 基因重叠，3' 区域与该基因 ...
The IGF2 gene provides instructions for making a protein called insulin-like growth factor 2. Learn about this gene and related health conditions.
