Searching…
Jan 15, 2026 · Complete information for MBD2gene (Protein Coding), Methyl-CpG Binding Domain Protein 2, including: function, proteins, disorders, pathways, orthologs, and expression.
Jan 6, 2025 · 本文将详细介绍MBD2基因的功能、作用机制、信号通路以及与疾病的关系。 MBD2基因位于18q21.2，编码甲基-CpG结合域蛋白2，是NuRD复合体的组成部分，参与染色质重塑和基因表达调控。
MBD2 and MBD3 are close relatives and probably descend via gene duplication from an ancestral MBD2/MBD3, that is present in some metazoans as for instance Caenorhabditis elegans and Drosophila (Marhold et al., 2004).
Jun 19, 2025 · This review discusses the role of MBD2 in regulating immune cell development and differentiation through epigenetic mechanisms, particularly DNA methylation and its regulatory components.
Apr 30, 2025 · 其中，MBD2不仅是核小体重塑和组蛋白去乙酰化酶（NuRD）复合体的核心组分，还具有特异性识别甲基化DNA的能力。 临床研究表明，MBD2在神经胶质瘤、宫颈癌、胰腺癌等多种人类恶性肿瘤中普遍呈现高表达状态，且其表达水平与肿瘤的生长转移密切相关。
Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capab...
Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capab...
