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pmc.ncbi.nlm.nih.gov
Detection of parC gene mutations associated with quinolone ...
Increasing levels of antibiotic resistance are complicating treatment for the sexually transmitted pathogen Mycoplasma genitalium . Resistance to fluoroquinolones is associated with mutations in the parCgene. Although...
www.nature.com
Discovery of seven novel mutations of gyrB, parC and parE in ...
Apr 30, 2020 · Only 2 point mutations were observed in parE, I444S (S. Paratyphi A) and S498T (S. Paratyphi B), which were novel. All parC and parE were detected with the concomitant presence of S83F in gyrA.
wenku.baidu.com
淋病奈瑟菌gyrA和parC基因喹诺酮耐药决定区突变与环丙沙星耐药相关性...
Sequencing analysis of gyrA revealed that all 50 isolates had mutation of S91F and 49 resistant isolates had mutation of D95G/A/N/E. Mutations in parCgene were at 85, 86, 87 and 91.
cn.sinobiological.com
PARC 基本信息 | Sino Biological
Jul 25, 2016 · PARC Protein Function Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule d...
zhuanlan.zhihu.com
脲原体属和人型支原体体外药物敏感性及其对喹诺酮类药物耐药机制分析...
目前脲原体属感染治疗多采用四环素类、大环内酯类和喹诺酮类抗菌药物。 随着抗菌药物的广泛使用，耐药现象日趋严重，尤其是喹诺酮类耐药比率不断升高。 喹诺酮类药物作用关键靶点包括DNA促旋酶和 拓扑异构酶 Ⅳ，这两者分别由gyrA/gyrB和parC/parE基因编码。
www.knowcat.cn
gyrA和parC基因突变与解脲支原体喹诺酮类药物耐药相关性研究 - 知猫论...
Jul 20, 2024 · 本研究分离了42株解脲支原体临床菌株并检测其对环丙沙星、氧氟沙星和司帕沙星3种喹诺酮类药物的耐药性，PCR扩增所有菌株gyrA和parC基因包括QRDR在内的核苷酸序列并直接测序，以探讨本地区解脲支原体gyrA和parC基因的QRDR突变与喹诺酮类药物耐药的相关性。
rs.yiigle.com
parC基因突变致环丙沙星不敏感化脓性链球菌及其同源性研究 - 中华检验...
发现1株在parC基因上Ser79Phe突变合并parE基因上371位丝氨酸突变为亮氨酸（Ser371Leu）的化脓性链球菌，但该菌株对环丙沙星的MIC未显著增高（MIC=4 mg/L）。