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The Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) stratifies severity of systemic lupus erythematosus (SLE).
All damage is scored from the time of SLE diagnosis onward regardless of whether or not the damage is attributed to lupus. SDI contains items that represent permanent, irreversible damage in a lupus patient.
The SDI is a composite COA that helps clinicians monitor the cumulative burden of SLE overtime by integrating multiple clinical observations across various organ systems into a single, standardized score that reflects...
Jun 1, 2025 · SLICC/ACR Damage Index (SDI) is widely used to estimate damage over time, has been validated in many settings and is predictive of long-term survival and quality of life in lupus patients.
为了评价 SLE患者的器官损害程度和预后，系统性狼疮国际临床协作组和美国风湿病学学会（SLICC/ACR）提出了SLE的损伤指数(表)，所提到的临床表现一般应持续6个月以上，以排除急性活动期的表现。
- 首次提出SLE达标治疗策略，目标为 DORIS缓解（完全缓解）或LLDAS（狼疮低疾病活动状态）。 - 达到LLDAS可显著降低器官损伤风险（SDI评分增加风险↓41%）和复发风险（重度复发风险↓55%）。
Page 1 SLICC/ACR Damage Index (SDI) Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index 6 months unless otherwise stated. Repeat episodes have o be ≥ 6 months apart to scor...
