Effect of Salt Substitution on Cardiovascular Events and Death
The SSaSS was an open-label, cluster-randomized trial that was conducted in 600 villages in the rural areas of five provinces in China — Hebei, Liaoning, Ningxia, Shanxi, and Shaanxi.
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The SSaSS was an open-label, cluster-randomized trial that was conducted in 600 villages in the rural areas of five provinces in China — Hebei, Liaoning, Ningxia, Shanxi, and Shaanxi.
The effects on cause-specific cardiac outcomes are reported here. Methods: SSaSS was an unblinded, cluster-randomised trial assessing the effects of potassium-enriched salt compared with regular salt among 20 995 Chin...
研究者建立了一系列模型,根据24小时尿液中的钠钾排泄量估算钠钾摄入量,分析归因于钠摄入减少和钾摄入增加的收缩压降幅占比。 结果发现,在SSaSS研究中,收缩压降低了3.3 mmHg,相应的24小时钠排泄量平均减少了 15.2 mmol,24小时钾排泄量平均增加了20.6 mmol。
The design of SSaSS was premised on the joint blood pressure-lowering effects of sodium reduction and potassium supplementation.
本研究采用了经典的24小时尿液收集的方法计算24小时的钠钾排泄量,并以此估算钠钾的日摄入量。 每日毅讯 + 在我国进行的著名的SSaSS研究(盐替代品和中风研究)报告了通过简单的高钾盐的替代治疗可以显著改善患者的心血管预后,特别是预防中风的发生。
SSaSS was an unblinded, cluster-randomised trial assessing the effects of potassium-enriched salt compared with regular salt among 20 995 Chinese adults with established stroke and older age and uncontrolled hypertension.
The SSaSS trial is of considerable scientific importance because vascular diseases remain the leading cause of premature death and disability around the world and the identification of new, low-cost, scalable interven...
研究者建立了一系列模型,根据24小时尿液中的钠钾排泄量估算钠钾摄入量,分析归因于钠摄入减少和钾摄入增加的收缩压降幅占比。 结果发现,在SSaSS研究中,收缩压降低了3.3 mmHg,相应的24小时钠排泄量平均减少了15.2 mmol,24小时钾排泄量平均增加了20.6 mmol。
研究将持续5年时间,期间对受试对象进行随访,记录脑卒中和其他心血管事件,还会采集尿样以检测钠和钾的含量。 武阳丰说:"以往的研究证实低钠盐可以降低血压,而SSaSS将是世界上规模最大的通过饮食干预预防脑卒中的研究。 "
Design, setting, and participants: The Salt Substitute and Stroke Study (SSaSS), an open-label, cluster randomized clinical trial, was conducted in 600 northern Chinese villages (clusters). Patients who self-reported ...