chaikoff效应

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Wolff-Chaikoff效应_百度百科

Wolff-Chaikoff效应指甲状腺内高浓度碘通过抑制过氧化物酶活性，减少酪氨酸有机化并阻断溶酶体释放，从而抑制甲状腺激素合成和释放的生理调节机制。

Wolff-Chaikoff Effect - an overview | ScienceDirect Topics

The Wolff-Chaikoff effect is the anti-thyroid effect caused by a rapid rise in circulating iodine. Excess iodide inhibits the function of thyroperoxidase by reducing iodide oxidation and organification, resulting in a...

Wolff–Chaikoff effect - Wikipedia

The Wolff–Chaikoff effect has been used as a treatment principle against hyperthyroidism (especially thyroid storm) by infusion of a large amount of iodine to suppress the thyroid gland.

什么是甲状腺的Wolff-Chaikoff效应？ - 好大夫在线

甲状腺内的碘不但参与甲状腺激素的合成，还可以通过Wolff-Chaikoff效应调节甲状腺激素的合成和释放，后者存在所谓的“脱逸现象”。

Wolff-Chaikoff Effect vs. Jod-Basedow Phenomenon

Homepage Endocrinology Endocrinology Wolff-Chaikoff Effect vs. Jod-Basedow Phenomenon Wolff-Chaikoff Effect: Iodine induced hypo thyroidism. Can occur in normal or hyperthyroid state. Can be used as treatment against ...

What is the Wolf-Chaikoff effect?

Mar 9, 2025 · The Wolff-Chaikoff effect is characterized by the thyroid gland's ability to block the uptake and organification of iodine, preventing overproduction of thyroid hormones that could lead to hyperthyroidism.

The Wolff-Chaikoff Effect. Panel A shows a propsed mechanism ...

Wolff-Chaikoff effect (WCE) is an acute physiologic response of the thyroid gland to high levels of iodine. The WCE is usually temporary, and the thyroid gland adjusts to high iodine levels...